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Artificial metal-based nanozyme
June 7 , 2025
14 hrs 0 min
25
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- Researchers at the Indian Institute of Science (IISc) have developed an artificial metal-based nanozyme.
- It can be used to clamp down on abnormal blood clotting caused by conditions like pulmonary thromboembolism (PTE).
- Under the normal circumstances, when blood vessel is injured, specialised blood cells called platelets get activated, and cluster together around the vessel to form protective blood clots.
- This process is known as the blood clotting cascade (haemostasis).
- But, conditions like PTE or diseases like COVID-19, are leading to over-activation of platelets.
- This triggers the formation of the excess clots in the blood vessel, contributing to thrombosis, a major cause of morbidity and mortality.
- The spherical-shaped vanadium pentoxide (V2O5) nanozymes mimic a natural antioxidant enzyme called glutathione peroxidase to reduce oxidative stress.
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