August 3 , 2025
17 hrs 0 min
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- A 38-year-old woman from Kolar near Bengaluru is the first known person with the ultra-rare CRIB blood group.
- CRIB stands for Chromosome Region Identified as Blood group and is part of the Indian Rare Antigen (INRA) system.
- This new blood group lacks a common antigen, making transfusions extremely complex and only compatible with CRIB-negative blood.
- The CRIB plays a crucial role in preventing Hemolytic Disease of the Fetus and Newborn (HDFN) during pregnancy.
- Fewer than 10 cases of CRIB blood group are known worldwide, marking it the rarest blood group to date.

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