Researchers have successfully demonstrated photosynthesis in mouse eye cells using a plant-derived nano-system called LEAF (Light-driven Engineered Artificial Thylakoid Factory).
Researchers introduced chloroplast-derived structures into mouse corneal cells, enabling them to produce energy-related molecules under light exposure.
LEAF functions as a temporary neo-organelle and generates ATP (Adenosine Triphosphate) and NADPH (Nicotinamide Adenine Dinucleotide Phosphate) using light energy.
The study explored its use in treating dry eye disease (Keratoconjunctivitis Sicca).
In preclinical mouse trials, LEAF therapy improved corneal health, increased tear film stability, and outperformed several standard treatments.