January 27 , 2026
10 hrs 0 min
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- The Scientists at the National Centre for Biological Sciences (NCBS), Bengaluru, developed a deep-learning tool called Disobind.
- Disobind predicts how intrinsically disordered proteins (IDPs) bind to their partners, even though these proteins do not have a stable 3D structure.
- It uses protein language models, trained on millions of protein sequences, without needing prior structural information.
- Disobind performed better than other tools like AlphaFold-Multimer and can be used alongside them for higher accuracy.
- The tool can help in disease research and drug discovery, including studies on immune signalling, cancer, and neurodegeneration.

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