TNPSC Thervupettagam

Protein AI Tool

January 27 , 2026 10 hrs 0 min 42 0
  • The Scientists at the National Centre for Biological Sciences (NCBS), Bengaluru, developed a deep-learning tool called Disobind.
  • Disobind predicts how intrinsically disordered proteins (IDPs) bind to their partners, even though these proteins do not have a stable 3D structure.
  • It uses protein language models, trained on millions of protein sequences, without needing prior structural information.
  • Disobind performed better than other tools like AlphaFold-Multimer and can be used alongside them for higher accuracy.
  • The tool can help in disease research and drug discovery, including studies on immune signalling, cancer, and neurodegeneration.

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