Science and Technology News

Polyendocrine Metabolic Ovarian Syndrome

May 18 , 2026 15 hrs 0 min 49 0

An international panel has renamed Polycystic Ovary Syndrome (PCOS) as Polyendocrine Metabolic Ovarian Syndrome (PMOS) to better reflect its biological complexity.
The earlier term PCOS was considered misleading, as many patients do not have actual ovarian cysts, which are actually immature follicles.
The new term PMOS highlights multiple hormone systems, including insulin, androgen, luteinising hormone (LH), and follicle-stimulating hormone (FSH).
It also places metabolic dysfunction at the centre, linking the condition with insulin resistance, diabetes, obesity, fatty liver disease, and cardiovascular risks.
Studies indicate that insulin resistance is present in nearly 70–80% of affected women, including those with normal body weight (“lean PMOS”).