TNPSC Thervupettagam

New Model to Develop Vaccines – Dept of Biotech

September 21 , 2019 152 days 338 0
  • The Department of Biotechnology (DBT) is to develop new influenza vaccines using a Controlled Human Infection Model (CHIM).
  • Under CHIM, volunteers who take part in trials will be infected with infectious viruses or bacteria but under expert supervision.
  • This approach will speed up the process whereby scientists can quantify whether potential vaccine candidates can be effective in people.
  • It also identifies the factors that determine why some vaccinated people fall sick and others do not.


  • To use CHIM protocols to study bacterial or enteric viruses (residing in the intestine) such as cholera or typhoid.
  • If successful, these would serve to create back-ups to the existing cholera and typhoid vaccines.

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